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Obsessive Compulsive Disorder
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Overcoming Anxiety (Home) > Obsessive Compulsive Disorder > Augmentation
Augmentation for Obsessive Compulsive Disorder
Augmentation is called for when there is partial or no response to the abovementioned approaches, i.e. combination of SSRIs (or SRIs) with other medications. To date, only two augmenting agents have been found to be effective in double-blind studies, i.e., risperidone and pindolol, which will be discussed below. However, many other augmenting agents have been tried and may be effective for some refractory patients. These include buspirone, lithium, trazodone, tryptophan and thyroid hormones.
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4. Immune Factors
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Study of autoimmune factors has been prompted by the association of OCD and the autoimmune disease of the basal ganglia, Sydenham’s chorea. This complication of rheumatic fever is accompanied [...]
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