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Obsessive Compulsive Disorder
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Overcoming Anxiety (Home) > Obsessive Compulsive Disorder > Augmentation
Augmentation for Obsessive Compulsive Disorder
Augmentation is called for when there is partial or no response to the abovementioned approaches, i.e. combination of SSRIs (or SRIs) with other medications. To date, only two augmenting agents have been found to be effective in double-blind studies, i.e., risperidone and pindolol, which will be discussed below. However, many other augmenting agents have been tried and may be effective for some refractory patients. These include buspirone, lithium, trazodone, tryptophan and thyroid hormones.
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1. Efficacy of Serotonergic vs Adrenergic Antidepressants
Efficacy of Serotonergic vs Adrenergic Antidepressants
While anecdotal reports have suggested that clinical benefit can be obtained with a range of antidepressant medications, [...]
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2. Pindolol
Pindolol
Pindolol augmentation (2.5 mg of pindolol, three times daily) with SSRIs is the second augmenting agent which has been found in [...]
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3. Biological Data
Other Biological Data
Sleep EEG and neuroendocrine studies have found several abnormalities similar to those seen in depression, such as decreased REM latency, non-suppression on the dexamethasone-suppression test and decreased [...]
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4. Methods of Treatment for Depression and Anxiety
Methods of Treatment for Depression and Anxiety
Often depression and anxiety by themselves are hard to live with and do not allow you to function well or get [...]
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