Obsessive Compulsive Disorder

Epidemiology

Comorbidity

OCD and Tic Disorder

OCD and Depression

OCD and Other Anxiety Disorders

OCD and Phobia

OCD and OCPD

OCD and Schizophrenia

Course and Prognosis

Etiology

Specific Clinical Response

Serotonin Antagonists

Pharmacological Challenges

Dopamine

Immune Factors

Brain Imaging Studies

Genetics

Other Biological Data

Behavioral Factors

Psychosocial Factors

Treatment of OCD

Efficacy of Serotonergic vs Adrenergic Antidepressants

Long Term Treatment of OCD

Drug Dosage

Psychological Approaches

Treatment Resistant OCD

Switching Medications

Augmentation

Risperidone

Pindolol

Other Options

Intravenous Clomipramine

Monoamine Oxidase Inhibitors

Last-line Therapies

Overcoming Anxiety (Home) > Obsessive Compulsive Disorder > Drug Dosage

Drug Dosage for Obsessive Compulsive Disorder

Higher doses of SSRIs and SRIs have been used in the treatment of OCD as compared to depression, but empirical data supporting this practice are scant. Two fixed-dose studies using fluoxetine and one Pan-European study with paroxetine found some advantage with using higher doses, while one fixed-dose study with sertraline has not. It seems reasonable to use higher doses in non-responders or when only partial relief is attained.




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Drug Dosage