Obsessive Compulsive Disorder

Drug Dosage for Obsessive Compulsive Disorder

Higher doses of SSRIs and SRIs have been used in the treatment of OCD as compared to depression, but empirical data supporting this practice are scant. Two fixed-dose studies using fluoxetine and one Pan-European study with paroxetine found some advantage with using higher doses, while one fixed-dose study with sertraline has not. It seems reasonable to use higher doses in non-responders or when only partial relief is attained.

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