A significantly higher concordance rate was found for monozygotic twins than for dizygotic twins . Some 35% of the first-degree relatives of childhood-onset OCD patients are also afflicted with the disorder . Although this high rate is possibly related to the early onset subtype, it nevertheless suggests a genetic component in OCD. Genetic research has yet to find abnormalities at the 5-HT transporter gene level. A study exploring the polymorphism of the promoter region of the gene for the 5-HT transporter failed to identify any differences between OCD patients and controls.

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