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Obsessive Compulsive Disorder
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Overcoming Anxiety (Home) > Obsessive Compulsive Disorder > Serotonin Antagonists
Serotonin Antagonists
Support for the importance of serotonin in the therapeutic response to SRIs in OCD was provided by a study in which the investigators administered the serotonin receptor antagonist, metergoline and placebo to 10 patients with OCD in a doubleblind crossover study . Patients receiving CMI on a long-term basis responded with greater anxiety to a four-day administration of metergoline when compared with the placebo phase.
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1. Brain Imaging Treatment Depression Anxiety Add
Brain Imaging Treatment Depression Anxiety Add
Reiman et al., using positron emission tomography (PET), noted an exaggeration of the asymmetrical (right greater than left) parahippocampal gyrus [...]
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2. Cognitive Models for Panic Disorder
Cognitive Models for Panic Disorder
Among cognitive models, there are Clark’s theory, Barlow’s false alarm theory and anxiety sensitivity theory. According to [...]
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3. Psychological Models
Psychological Models
Psychodynamic, behavioural and cognitive psychological models of panic disorder have been formulated.
Psychodynamic Models
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4. Monoamine Oxidase Inhibitors
Monoamine Oxidase Inhibitors
The earliest placebo-controlled evidence for the efficacy of this therapeutic class was obtained with phenelzine, and its efficacy is well established Concerns about its tolerability and safety, [...]
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