Post-Traumatic Stress Disorder

The Spectrum of Post-Traumatic Syndromes

The Basic Stress Responses: Defence and Inhibition

Somatic Stress Syndromes

The Generation of Somatic Symptoms

Diagnostic Integration

Syndromal Diagnosis

Predictors and Risk Factors

Lifetime Development

Comorbidity

Overcoming Anxiety (Home) > Post-Traumatic Stress Disorder > Diagnostic Integration

Diagnostic Integration

Diagnostic Taxonomy-Matrix Diagnosis

The conceptual difficulties of describing the functional and somatoform syndromes listed in the previous paragraph have also caused problems in arranging them in the disease taxonomies that are commonly in use. The DSM tries to integrate the somatic, psychological, and social dimensions at the price of creating comorbidity . I see only one way to reach integration, that is by constructing a matrix of dimensions that follows the natural development of the human species (phylogeny) and individuals (ontogeny).

All the observable aspects of an individual’s functioning should then be broken down into dimensions based on these developmental lines. It is a matrix constructed for the full integrity of the individual patient. Semantically, it corresponds to the meaning of a matrix in mathematics. The genetically determined, unchangeable biological properties are at the basis of this system. Imprinting and learning are processes directly based on the genetic make-up of an individual. Imprinting is the creation of read-only-memories (ROMs), a biological parallel of computer ‘‘firmware’’. Learning is the adaptation and neural plasticity of functional circuits in response to repeated activation. Associative memory is another aspect of learning. Associations are acquired and, then, automated programmes. Acquisition of this dimension starts during ontogeny as the first layer over Diagnostic Matrix of Dimensions

  1. Genetic floorplan
    • Structural floorplan (embryology/anatomy)
    • Homeostatic physiology
    • Psychophysiology (inborn responses to adaptational challenges)
  2. Acquired automated mechanisms (neuromotor/neurohumoral output, sensory input)
    • Organising effects
    • Imprinting (Read Only Memory)
    • Long-term potentiation/dendritic plasticity
    • Association
  3. Declarative faculty
    • Reflexive consciousness
    • Emotional development
  4. Complex language dependent systems
    • Cognition: science, logic, mathematics, philosophy
    • Groups/systems: politics

the inborn properties. Intrusive memory of sensory input and imprinted or amplified physiological memory belong to this dimension, as well as impulsiveness or temperament. From a heuristic point of view, it seems logical to separate linguistic development from the second dimension, considering the phylogeny of homo sapiens sapiens.

Reflexive consciousness and the development of emotional expression are representations of the declarative faculty including relational behaviour, literature, etc. Alexithymia is a description of incomplete or inhibited emotional development at the declarative level. It is characteristic of somatoform disorders and functional or psychophysiological syndromes. Psycho-physiological syndromes as listed in the paragraph on somatic stress syndromes can thus be seen as phylogenic and ontogenic precursors of more differentiated psychiatric syndromes.

Complex language-dependent systems can be seen as the present ultimate development of phylogeny and ontogeny. They constitute what we use to call human‘‘civilisation’’ including all aspects of science, philosophy and political systems, structures that are based on semantically explicit cognition. Although scientific theory development requires economy in calling in assumptions or abstractions, it seems appropriate and efficacious to categorise this level of development in a separate dimension, making a link with sociology.

This diagnostic matrix is a dimensional analysis slightly different from Van Praag’s proposal for functionalisation, verticalisation or ‘‘two-tier’’ diagnosing and more extensive but permits inclusion of his idea. It allows us to break down pathology at the level of the genome or allostatic physiology and phenotypical expressions or changes by organising effects of hormones and stressors, long-term potentiation, imprinting, plasticity, apoptosis, learning in all its aspects, deviant behaviour and irresponsible use of scientific progress or political power, genocide, etc.




More Articles
1. Benzodiazepines (BDZs): Anxiety, Medication and Side Effects
Benzodiazepines (BDZs): Anxiety, Medication and Side Effects Among BDZs, alprazolam and clonazepam have been reported to be efficacious in the treatment of PD. They [...]

2. Biological Findings for Panic Disorder
Biological Findings for Panic Disorder The principal research approaches when investigating possible biological mechanisms underlying PD are laboratory studies using provocative agents and pharmacological and [...]

3. Selective Serotonin Re-uptake Inhibitors (SSRIs)
Selective Serotonin Re-uptake Inhibitors (SSRIs) During a recent NIMH Algorithm Development Meeting, the expert panel reached the conclusion that the SSRIs [...]

4. Augmentation for Obsessive Compulsive Disorder
Augmentation for Obsessive Compulsive Disorder Augmentation is called for when there is partial or no response to the abovementioned approaches, i.e. combination of SSRIs (or SRIs) [...]


ADD YOUR LINK HERE

Bookmark This Page:

Add to Favorites

Add to Del.icio.us

Send to a Friend

Resources:

Alternative Health

Anxiety

Depression

Health

Mental Health

Nutrition

Psychotherapy

Self Help

© Overcoming Anxiety .org | SITEMAP | Resources

RSS Feed

About Us | Contact Us | Link to Us

Terms of Service, Privacy Policy and Disclaimer

Diagnostic Integration