Benzodiazepines Action and Effects in Anxiety

Both alprazolam and clonazepam have demonstrated their efficacy in a number of open studies. Nevertheless, it is known that benzodiazepines (BDZs) are contra-indicated in patients who abuse alcohol (a condition that often co-occurs with SP), and that the chronic use of these drugs can cause physical dependence. Thus, they are not considered a good choice for monotherapy for long-term use in anxiety disorders such as SP. BDZs can only be useful either in association with other drugs, such as antidepressants or as purely symptomatic remedies for sporadic use.

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